
Description of Apigenin Powder:
Chamomile extract is the dried whole herb extract of Matricariachamomilla L., a plant of the Asteraceae family. It mainly contains active ingredients such as flavonoids, saponins, polysaccharides, and volatile oils. It has anti-inflammatory, antifungal, and antispasmodic effects. Due to its multiple medicinal effects, it has been used as an ingredient in medicinal cosmetics. Ointments, creams, and lotions containing chamomile volatile oils have been used in Europe to treat various skin diseases.
Specification of Apigenin Powder:
| Item | Content |
|---|---|
| Botanical Source | Matricaria chamomilla L. |
| Part Used | Whole Grass |
| Main Component | Apigenin |
| Specification | 10:1, 20:1, 30:1, 50:1 or Apigenin 1%~98% |
| Appearance | Brown yellow to light yellow powder |
| Test Methods | TLC (Thin-layer chromatography), HPLC (High-performance liquid chromatography) |
| Packaging | Less than 5KG: Double-layer plastic packaging with aluminum foil outer layer; More than 25KG: Cardboard drum; Standard packaging: 25KG/drum |
| Storage Conditions | Sealed, light-protected, dry, cool, and well-ventilated place |
| Shelf Life | Two years |
Effects of Apigenin:
- Apigenin’s main effect is as an anxiolytic and sleep aid: by binding to the GABAA receptor, it is fast-acting and non-addictive, and studies have shown that a dose of 50mg can improve sleep.
- It is also an anti-inflammatory antioxidant with a high ORAC value that inhibits NF-κB and COX-2, reducing inflammation.
- Studies have shown that apigenin also has neuroprotective effects, reducing beta-amyloid deposition in Alzheimer’s disease and inhibiting alpha-synuclein aggregation in Parkinson’s disease.
- In addition, it has shown potential in anti-cancer and cardiovascular protection.
Example of a typical formulation of apigenin:
| Ingredient | Dosage | Function |
|---|---|---|
| Apigenin | 50mg | Activates GABA receptors, shortens sleep onset time |
| L-Theanine | 200mg | Enhances alpha brain waves, relieves anxiety |
| Magnesium Glycinate | 100mg | Regulates neuromuscular relaxation |
| Melatonin (Optional) | 1mg | Regulates sleep-wake cycle (fast-acting) |
| ITEM | SPECIFICATION | RESULT |
|---|---|---|
| Ratio | 20:1 | Conform |
| Apigenin | NLT98% | 98.85% |
| Appearance | Light yellow powder | Conform |
| Odor | Characteristic | Conform |
| Mesh Size | 100% pass 80mesh | Conform |
| Ash Content | NMT 5.0% | 4.22% |
| Loss on drying | NMT 5.0% | 3.62% |
Heavy metal and microbiological analysis:
| ITEM | SPECIFICATION | RESULT |
|---|---|---|
| Chemical Control | ||
| Lead | NMT 2 ppm | Conform |
| Cadmium | NMT 1 ppm | Conform |
| Mercury | NMT 1 ppm | Conform |
| Arsenic | NMT 2 ppm | Conform |
| Microbiological Tests | ||
| Total Plate Count | NMT 1,000 cfu/mg | Conform |
| Yeast & Mold | NMT 25 cfu/mg | Conform |
| E.Coli. | NMT 40 MPN/100g | Conform |
| Staphylococcus | Negative | Conform |
| Conclusion | Product Conforms to Specifications |
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